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Those ideas included DNA sequencing, which he first cut a check for in the 90s, and leveraging the immune system to tackle cancer. “It’s like the least trendy idea in the world,” Nelsen told me. And Bob’s hit.”We'll e-mail you a link to set a new password. The company has trimmed nearly €1 billion in annual expenses so far in 2020.With its trials and pricing set, Pfizer has pulled back the curtain on the long-range commercial strategy for its COVID-19 vaccine.The drug could be a rival to Pfizer’s potential blockbuster Vyndaqel (tafamidis). Investors told them to come back with more data, pharmaceutical executives said they’re in the wrong game — too little money to be made fighting infectious disease. But BridgeBio also called Saunders a “dealmaker,” hinting that drug-launch advice isn’t all the company’s looking for from an executive known for pulling off big M&A.Then in October, the biotech was denied a merger deal by its Eidos unit to acquire the remaining 34% of Eidos shares it doesn’t already own, even though it raised its offer twice to the final tender equivalent to 1.5 BridgeBio shares for each piece of Eidos share. And there was a cancer drug as well as an HIV program in the mix of the nixed.Unlock this story instantly and join 86,000+ biopharma pros reading Endpoints daily — and it's free.What do you charge for a Covid-19 vaccine? By the look of Saunders’ appointment, it just may be.Sanofi's cost cuts are adding up, execs said in an update Wednesday. “Most of them just didn’t get it. But there are apparently two places in which the company apparently doesn’t want its presence known — its Cambridge, MA headquarters, and its Norwood, MA manufacturing plant.In a review of R&D activities for Q2 Tuesday evening, Amgen noted:Saun­ders may find the lat­est roast­ing was just a mod­est pre­lude to what comes next.Re­gard­ing the stock, in­vestors have in­di­cat­ed to us that if ra­pastinel fails there could be (and should be) in­creased pres­sure on man­age­ment and/or the Board to im­ple­ment some type of change.Louis Picker and Klaus Früh, professors at Oregon Health & Science University, had by then spent 5 years running around the country in search of funding for their startup, TomegaVax, and Früh, at least, was nearing wit’s end. Shingrix sales in Q2 plummeted by half from Q1 levels, and recovery of vaccination rates remains slow amid the pandemic.On the future launch side, perhaps the most important asset at BridgeBio is BBP-265 (AG10), in phase 3 clinical development by its subsidiary Eidos Therapeutics for the rare heart disorder transthyretin amyloidosis cardiomyopathy (ATTR-CM).Less than two months after Allergan was officially taken in by AbbVie, its last helmsman, Brent Saunders, has landed on the board of a young biotech that recently pulled off a large IPO.In addition to a long list of drugs for genetic diseases, BridgeBio also has infigratinib, an FGFR inhibitor its subsidiary QED Therapeutics is testing in cancer.